The SDLP and the DUP could be the biggest losers if the provisional recommendations of a new boundary review are adopted.
Northern Ireland is due to lose two of its 18 Westminster seats with South Belfast and East Derry being the two constituencies most affected.
But since the same boundaries are used for Stormont elections as Westminster ones, the changes will also impact on party numbers in the Assembly where six MLAs are elected from each constituency.
SDLP MP Alasdair McDonnell's South Belfast seat will go, divided between Belfast South West and South East seats.
Mid-Ulster, East Derry and West Tyrone are reorganized into two new seats called Glenshane and Mid-Tyrone.
While Sinn Féin would lose one of their Tyrone MPs the party would be in a good position to win DUP MP Gregory
Campbell's East Derry seat.
Other changes include the Ards Peninsula shifting from Strangford to North Down and much of Ballymena moving from North Antrim to a new Mid-Antrim seat. North Belfast would be expanded to include the Shankill area.
There is now a 12-week consultation period for politicians and the voters to get the chance to tell the boundary commissioners what they think of their new constituencies.
South Belfast MP Alasdair McDonnell said his seat had been "shredded."
"From a status, from an authority, and from a clout in political terms, Belfast is now a smaller place as a result of these boundary changes." he said.
Sinn Féin MP for West Tyrone, Pat Doherty, said the party would use this period for "look at and study" the proposals.
"We will have to examine all of this. The consultation period has been laid out that includes the public hearings and we will avail of all that," he added.
